Recommended Articles. Klebsiella pneumonia usually results from aspiration of colonizing oropharyngeal microbes into the lower respiratory tract. (2007) ISBN:B0011ZYZR2. Seventy of Klebsiella pneumoniae isolates had been collected from some Hospitals in Baghdad city from October to December 2017. Unable to process the form. A helpful feature which may help to distinguish from pneumococcal pneumonia is that Klebsiella pneumonia develops cavitation in 30-50% of cases (in comparison, cavitation is rare in pneumococcal pneumonia). J Comput Assist Tomogr. The 70 isolates were taken from diverse clinical specimens. Unable to process the form. All rights reserved. It is one of the causes that could be suspected when there is cavitatory pneumonia +/- a bulging fissure sign. (1968) Diseases of the chest. The spectrum includes. 2010;83 (994): 854-60. Klebsiella pneumoniae is among the most common Gram-negative bacteria encountered by physicians worldwide and accounts for 0.5-5.0% of all cases of pneumonia 2. Path. Klebsiella pneumoniae is a bacterium that normally lives inside human intestines, where it doesn't cause disease.. ADVERTISEMENT: Supporters see fewer/no ads, Please Note: You can also scroll through stacks with your mouse wheel or the keyboard arrow keys. The Post-operative Abdomen - Surgicel … Okada F, Ando Y, Honda K et-al. After that, a 6-week course of amoxicillin-clavulanate (1 g every 12 h) was substituted. Hansell DM. It is an important type of pneumonia because of its severity, high incidence of complications, and elevated mortality [1]. Klebsiella species are a Gram-negative rod shaped bacteria belonging to the Enterobacteriaceae family. This occurs early and progresses quickly. 01 Jul 2011 Radiology. It has a high mortality rate of approximately 50% even with antimicrobial therapy. A helpful feature which may help to distinguish from pneumococcal pneumonia is that Klebsiella pneumonia develops cavitation in 30-50% of cases. Cavitary pulmonary disease. 2. Klebsiella pneumoniae(K. pneumoniae) is a Gram-negative, non-motile, capsulated, gas-producing enteric bacillus widely found in nature, and it belongs to the normal flora of the human oral cavity and intestine. 1995;19 (2): 176-81. 2000 Oct;63(10):721-8. the Western countries, Klebsiella pneumoniae invasive syn-drome (KPIS) should be alerted when patients present atypi-cal vague symptoms including fever, chill, nausea, vomiting, and right upper quadrant tenderness. Antibiotics sensitivity test was carried out toward 10 antibiotics using discs diffusion method. Also, lobar expansion is not specific for Klebsiella infection. Microbiol. Often there can be extensive lobar opacification with air bronchograms. Klebsiella pneumoniae, a gram-negative organism, is an emerging common cause of PLA, particularly in patients with poorly controlled diabetes mellitus and without any pre-existing liver disease. Klebsiella pneumonia | Radiology Reference Article | Radiopaedia.org. bulging of the horizontal fissure in this case) is less common nowadays with modern antibiotic treatment. Klebsiella pneumoniae is a gram negative organism that usually affects people with alcoholism or chronic debilitating diseases (similar to other gram -ve pneumonias). Conversely, various pathogens give rise to identical radiologic findings; e.g., bronchopneumonia can be caused by, for example, Staphylococcus aureus, Klebsiella, Proteus, or Pseudomonas. Coronavirus: ... 2 Division of Diagnostic Radiology, Department of Diagnostic and Therapeutic Radiology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand. Among these, sporadic hvKp-related community-acquired pneumonia (CAP) is an acute-onset, rapidly progressing disease that can likely turn fatal, if left untreated. by Wenlie Xie and Huixuan Jia. 27-05-2014 - Klebsiella pneumonia is refers to a pneumonia resulting from an infection from the organism Klebsiella pneumoniae. Sputum analysis grew Klebsiella pneumoniae. © 2005 - 2021 WebMD LLC. Extensive right upper lobe consolidation, with bulging of the horizontal fissure. They are commonly found in the environment and in … (2009) ISBN:0723434964. The three most common patterns are lobar pneumonia, bronchopneumonia, and interstitial pneumonia. The past 3 decades have seen the emergence of an invasive liver abscess syndrome caused by Klebsiella pneumoniae that may manifest with metastatic infection to the eye, brain, or lung [1, 2]. Introduction . Less common forms of infection include cellular bronchiolitis, septic embolism, miliary infection, and lung abscess. 87: 319. On CXR, consolidation is lobar and resembles streptococcus pneumonia. Klebsiella pneumoniae (K. pneumoniae) are bacteria that normally live in your intestines and feces. Klebsiella pneumoniae- Pathogenicity and Clinical Manifestations. Check for errors and try again. There tends to be a higher prevalence in older patients with alcoholism and debilitated hospitalized patients 3. Complications of Klebsiella pneumonia: CT evaluation. 53 (4): 481-6. Massive necrosis (pulmonary gangrene) is a recognized complication. Check for errors and try again. E.Brant MW, A.Helms MC. {"url":"/signup-modal-props.json?lang=us\u0026email="}. In comparison, cavitation is rare in pneumococcal pneumonia. 7. This organism can cause extensive pulmonary necrosis and frequent cavitation 1. In the setting of pneumonia, infection with K. pneumoniae is confirmed by either sputum culture analysis, blood culture analysis or midstream urine depending upon the illness. 3. However, in general, the type of microorganism implicated in pneumonia can be identified (bacteria, viruses, or fungi). Klebsiella is also responsible for a significant number of community-acquired infections. Necrotizing pneumonia can occur as a complication 6. These infections are particularly a problem among neonates, elderly and immunocompromised individuals. Klebsiella spp. On CXR, consolidation is lobar and resembles streptococcus pneumonia. ADVERTISEMENT: Radiopaedia is free thanks to our supporters and advertisers. ADVERTISEMENT: Radiopaedia is free thanks to our supporters and advertisers. ; Material is inoculated into blood agar and Mac Conkey agar medium and incubated aerobically. 4. K. pneumoniae is found in the normal flora of skin, mouth and intestines, where it does not cause disease. Nineteen cases were seen in the first half of 1958. Massive necrosis (pulmonary gangrene) is a recognized complication. 5. Gadkowski LB, Stout JE. 61-year-old woman with a long-standing history of alcohol abuse presented with a sudden onset of cough, pleuritic chest pain, dyspnea, fever, and rigors. Klebsiella pneumoniae is a Gram-negative, non-motile, encapsulated, lactose-fermenting, facultative anaerobic, rod-shaped bacterium.It appears as a mucoid lactose fermenter on MacConkey agar.. Klebsiella pneumoniae was first described by a German microbiologist and pathologist Carl Friedländer in 1882. 6. The hypervirulence of these novel community-acquired strains is mediated in part by their hypermucoviscous phenotypes associated with K1 and K2 capsule serotypes [ 3–5 ]. K pneumoniae monomicrobial liver abscesses were associated with diabetes mellitus (P <.001), higher blood glucose levels at admission (P <.05), predominantly solid US appearances (P <.001), irregular or indistinct lesion margins (P <.05), less than 2 mL of pus aspirated (P <.001), and longer duration of antibiotic treatment (P <.05). Clin. These bacteria are harmless when they’re in … Authors S ... diagnostic radiology studies, therapeutic modalities and risk factors associated with mortality were studied. Klebsiella species cause a wide range of diseases including pneumonia, urinary tract infections (UTIs), bloodstream infections and sepsis. Klebsiella pneumoniae renal abscess Zhonghua Yi Xue Za Zhi (Taipei). Imaging of Diseases of the Chest. The bacterium typically colonizes human mucosal … It is not possible radiologically to pinpoint the causative organism. (1882) Virchow Arch. Acute Klebsiella pneumoniae pneumonia alone and with concurrent infection: comparison of clinical and thin-section CT findings. [12,17] Aspiration pneumonia should always be suspected if the infiltrates are present bilaterally in the dependent or posterior portions of the lungs. Anat. Klebsiella [kleb−see−ell−uh] is a type of Gram-negative bacteria that can cause different types of healthcare-associated infections, including pneumonia, bloodstream infections, wound or surgical site infections, and meningitis. Klebsiella pneumoniae is a gram negative organism that usually affects people with alcoholism or chronic debilitating diseases (similar to other gram -ve pneumonias). CHEST Journal. 2008;21 (2): 305-33, table of contents. There has been a considerable increase in the incidence of this type of pneumonia beginning in 1954 and reaching a peak in 1956, with 21 cases. Continuous improvement of the lesion was found on follow-up chest X-rays. There can b… 769-776. 1 - 5 Although single case reports discuss the clinical presentation of pneumonia caused by Escherichia coli or Actinobacillus spp., 6, 7 to the authors’ knowledge no large retrospective studies describe the … The disease is often overlooked in the Western physicians due to its rarity. Volume: 242 Issue: 3 pp. Diagnosis: Klebsiella pneumonia (aka Friedländer’s pneumonia) - Images, diagnosis, treatment options, review - Thoracic Imaging Case. Br J Radiol. Mosby Incorporated. Friedlander's pneumonia. Lippincott Williams &Wilkins. On CXR, consolidation is lobar and resembles streptococcus pneumonia. Pulmonary infection can also be classified into several radiologic and pathologic patterns according to its morphologic features. In nosocomial pneumonia, patchy bronchial pneumonia is the most common finding and is likely caused by Gram-negative pathogens, especially Pseudomonas or Klebsiella. Klebsiella pneumoniae is a gram negative organism that usually affects people with alcoholism or chronic debilitating diseases (similar to other gram -ve pneumonias). Invasive community-acquired infections, including pyogenic liver abscesses, caused by hypervirulent Klebsiella pneumoniae (hvKp) strains have been well recognized worldwide. The presence of gram-negative rods in Gram-stained smears suggests Klebsiella; they maybe capsulated and non-sporing. Hansell DM. Ono A. 1. Volume: 260 Issue: 1 pp. (2009) ISBN:0723434964. 2011;140 (4_MeetingAbstracts): . To retrospectively compare the computed tomographic (CT) features of liver abscesses caused by Klebsiella pneumoniae with those caused by other bacterial pathogens. Klebsiella pneumonia, also known as Friedländer pneumonia, refers to pneumonia resulting from an infection from the organism Klebsiella pneumoniae. … This occurs early and progresses quickly. are commonly implicated as a cause of bacterial pneumonia in horses, but few reports describe the clinical presentation and progression of disease attributable to this organism. CT Appearance of Pyogenic Liver Abscesses Caused by Klebsiella pneumoniae. Chronic Klebsiella pneumonia: a rare manifestation of Klebsiella pneumonia. The Brant and Helms Solution. Pyogenic Liver Abscesses Caused by Klebsiella pneumoniae: US Appearance and Aspiration Findings. Radiology 2011. A report of 11 cases and appraisal of antibiotic therapy. Results: The mean age was 58.7 years and the male to female ratio was 10:14. Figure Klebsiella pneumoniae liver abscess cases (n=123) in an outpatient parenteral antibiotic therapy (OPAT) cohort in Singapore, 2006–11 (n=2229) View Large Image Figure Viewer; Download Hi-res image Download (PPT) Roughly 70% of patients with K pneumoniae abscesses were men. There can be variable features on chest HRCT which can also depend on current other organisms. Klebsiella pneumoniae is a Gram-negative bacteria and a well-known cause of community-acquired pneumonia, which accounts for less than 5% of all cases of pneumonia. Moon WK, Im JG, Yeon KM et-al. Hoffman NR, Preston FS. 129-138. See additional information. Rev. Risk factors for Klebsiella pneumonia include alcoholism, diabetes mellitus, and COPD. {"url":"/signup-modal-props.json?lang=us\u0026email="}. WebMD does not provide medical advice, diagnosis or treatment. 8. Imaging of Diseases of the Chest. Often there can be extensive lobar opacification with air bronchograms. ADVERTISEMENT: Supporters see fewer/no ads. Friedlander, C. Über die Pseudomyceten bei der acuten fibrinösen Pneumoniae. Lobar expansion (e.g. Klebsiella pneumonia is a necrotizing process with a predilection for debilitated people. VCU Department of Radiology VCU Medical Center. This occurs early and progresses quickly. K. pneumoniae is also a well-known cause of community-acquired pneumonia. The chest films of 58 patients with proved pneumonia due to Pseudomonas, Klebsiella, Enterobacter, Escherichia coli, Proteus, or Bacteroides were reviewed.Pseudomonas pneumonia was characterized by diffuse alveolar involvement with rapid progression to extensive macrocavitation. A helpful feature which may help to distinguish from pneumococcal pneumonia is that Klebsiella pneumonia develops cavitation in 30-50% of cases (in comparison, cavitation is rare in pneumococcal pneumonia). Mosby Incorporated. K. pneumoniaewas first discovered by Friedlander in 1882 and considered to be responsible for a severe form of lobar pneumonia. Radiology 2007. All K. pneumoniae isolates were identified based on API 20 E and Vitek2 compact system. Klebsiella pneumoniae is a gram-negative, encapsulated, non-motile bacterium that is found in the environment and has been associated with pneumonia in the alcoholic and diabetic patient population. Klebsiella pneumoniae is a Gram-negative bacillus with worldwide distribution that usually causes respiratory and urinary tract infections, ... Four weeks after admission, following discussion with Radiology, a thoracic CT scan was performed for subsequent biopsy of one of the pulmonary lesions. Since 1950, 76 proved cases of pneumonia due to Staphylococcus aureus have been seen at the Los Angeles County Hospital. Massive necrosis (pulmonary gangrene) is a recognized complication. Chronic Klebsiella pneumonia was diagnosed and ceftazidime was changed to ceftriaxone 1 g every 12 h for 2 weeks. Case of the Week: August 27-September 3, 2009. It is one of the causes that could be suspected when there is cavitatory pneumonia +/- a bulging fissure sign. The organism Klebsiella pneumoniae was first described by German microbiologist Carl Friedländer (1847-1887) in 1882, in a series of patients with Klebsiella pneumonia 7,8. Cellular bronchiolitis, septic embolism, miliary infection, and lung abscess using diffusion. Is a recognized complication of Klebsiella pneumoniae: US Appearance and Aspiration Findings, Ando Y, K! That, a 6-week course of amoxicillin-clavulanate ( 1 g every 12 h was! 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