Do not take sodium clodronate at the same time as food or other medications because they may prevent its absorption. Background. Clodronate. Clodronate. Back to top. Company: Berlex, Inc. Clodronato (Oral; Injetável) (substância ativa) Referência: Bonefós (Bayer). Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for SODIUM CLODRONATE. It is used to treat high calcium levels in patients with cancer. CLODRONATO ABC Active Ingredient Clodronate 100 mg/3.3 ml injectable solution - 6 ampoules 100 mg/3.3 ml injectable solution - 12 ampoules 300 mg/10 ml solution for infusion I.V. Back to top. inibe a reabsorção óssea que leva a aumento do cálcio no sangue. Generic name: clodronate. Diluente: Cloreto de Sódio 0,9% ou Glicose 5%. 1997 Oct 15;80(8 Suppl):1691-5. Brand names and generic names are differentiated by the use of capital initials for the former.. See also the list of the top 100 bestselling branded drugs, ranked by sales. Special pediatric considerations are noted when applicable, otherwise adult provisions apply. 1.6 g daily in 1–2 divided doses, then increased if necessary up to 3.2 g daily in 2 divided doses. Inicial DA = Draining area of lymph node. This site complies with the HONcode standard for trustworthy health information: verify here. Take this medication 1 to 2 hours (depending on your brand) before or 1 to 2 hours after taking any products that contain aluminum, calcium, iron, magnesium, or zinc. (claw-DROE-nate) is a drug that is used to treat cancer which has spread into the bones (bone metastases). A dose máxima diária é de 3200 mg. A duração do tratamento é, em geral, de 6 meses. Sodium clodronate is a bisphosphonate and is prescribed for problems which affect bones. Suggested Pages. Clodronate also treats the weakening in the bones when cancer has spread to the bones from another part of the body. Excipients Capsules. Disclaimer. O MedicinaNET é o maior portal médico em português. Permanecemos com suporte aos nossos inscritos através do e-mail Brand name: Bonefos. Macrophage Depletion Kit (Mannosylated) In other countries is prescribed as a bone resorption inhibitor and antihypercalcemic agent. It is a capsule that you take by mouth. Clodronato dissódico (solução) 1500 mg/25 mL – Infusão intravenosa. - 6 ampoules Brand Names: Canada. LEGENDS: AL = Alveoli in lung. Reações mais comuns (sem incidência definida): Fechamento de Forame Oval Patente ou Anticoagulação em Comparação Com Antiplaquetários Após AVC, Diretriz da SBC Para Gravidez na Mulher Cardiopata (parte 5/17), Risco de Suicídio e Morte Cardiovascular Após o Diagnóstico de Câncer, 6 Medicamentos Utilizados no Manejo Das Neoplasias, Infecção Latente Por M. Tuberculosis e Atualização Terapêutica - Dr. Marcelo Litvoc - 50 Min - 09/1, Estratégia Transfusional Liberal ou Restritiva Após Cirurgia de Quadril em Pacientes de Alto Risco, Suporte Avançado - Dr. Ricardo Casalino Sanches de Moraes - 52 Min - 11/10, 3.4 Medicamentos Utilizados no Tratamento da Gota, Manual de Implementação do Checklist: Parte II - Antes de Iniciar a Cirurgia. Generic names: clodronate disodium, clodronic acid disodium tetrahydrate; Brand names: Clasteon, Clastoban, Climaclod, Clodeosten, Clodran, Clodron, Clody, Difosfonal, Disdual, Lodronat, Loron, Lytos, Mebonat, Moticlod, Niklod, Ossiten, Ostac, Osteonorm, Osteostab, Sindronat; References ↑ Read More. Clodronate, Disodium Salt, CAS: 22560-50-5, is A bisphosphonate apoptosis inducing agent. Estabilidade após diluição com Cloreto de Sódio 0,9% temperatura ambiente (15 - 25°C): 6 horas. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. It is used to stop bone loss. Description and Brand Names. What is this drug used for? Clodronate is also used to treat cancer that has spread to bones (bone metastases) due to different types of tumours. THE GOOD NEWS is that there is finally an effective treatment for bone cancer—a drug named clodronate. BM = Bone marrow. Clodronate belongs to a family of medications known as bisphosphonates. Clodronate binds to calcium and inhibits osteoclastic bone resorption and hydroxyapatite crystal formation and dissolution, resulting in a reduction of bone turnover. The terminal elimination half-life may exceed a year as clodronate bound to bone is slowly released. •doses em termos de Clodronato dissódico. Clodronato dissódico tetraidratado equivalente a clodronato dissódico. This content does not have an English version. Cápsula 400 mg: Bonefós Uso injetável. Clodronic acid is approved for human use in Canada and Australia, the United Kingdom, where it is marketed as Bonefos, Loron, Clodron and in Italy as Clasteon, Difosfonal, Osteostab and several generics. Site designed by Pharma Professional Services and developed by Hasan Computing Systems. Bonefos [DSC]; Clasteon. Vaccine updates, safe care and visitor guidelines, and trusted coronavirus information, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Clodronic Acid (Oral Route, Injection Route), FREE book offer – Mayo Clinic Health Letter, New Year Special -  40% off – Mayo Clinic Diet Online. MedicinaNET - Todos os direitos reservados. It is also used to treat a high level of calcium in the blood that may occur with some cancers. Manufacturer advises avoid. Dermatológico: hipersensibilidade na pele. Sodium clodronate is used with other drugs to reduce the breakdown of bone caused by cancer that has spread to the bones. CAS: 22560-50-5, 7 mg/mL . This medicine is available only with your doctor's prescription. Cited in 1 publications Tribo™ Human IFN gamma ELISA Kit; Tribo™ Human β2-microglobulin ELISA Kit; Human TNFꭤ ELISA kit; 1 step and 1hr; Fast Human TGF-β1 ELISA Author information: (1)World Health Organization Collaborating Centre for Metabolic Bone Diseases, Department of Human Metabolism and Clinical Biochemistry, University of Sheffield Medical School, United Kingdom. Brands / Trade Names of Clodronate. All products: If you have an allergy to clodronate … Each capsule contains the equivalent of … This multi-page article lists pharmaceutical drugs alphabetically by name. Clodronate Synthesis Reference No information avaliable Clodronate. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. inibidor da reabsorção óssea [pirofosfato (derivado); ácido clodrônico (sal do); bifosfonato]. Advertising revenue supports our not-for-profit mission. Clodronate is a medicine used to treat a high level of calcium in the blood caused by changes in the body that happen with cancer. Clodronate, Disodium Salt - CAS 22560-50-5 - Calbiochem 1 Product Result | Match Criteria: Product Name EY = Eye. Parecoxib. Share this page on Facebook Share this page on Twitter Share this page on LinkedIn Share this page by email Share this page by URL. Perspectives from an Equine Expert Panel on Clodronate Use in Horses. Diluente: Cloreto de Sódio 0,9%. geniturinário: eliminação de proteínas pela urina; insuficiência renal aguda após administração intravenosa. All rights reserved. Lipid composition: phosphatidylcholine and cholesterol. Volume: 500 mL. • doses em termos de Clodronato dissódico. What do I need to tell my doctor BEFORE I take this drug? Em função da pandemia do Coronavírus informamos que não estaremos prestando atendimento telefônico temporariamente. Share this page. inflamação aguda do estômago ou intestino; diminuição da função renal. Clodronate has been extensively used in patients with advanced breast cancer, and is generally well tolerated. Clodronate RX_link No information avaliable Clodronate fda sheet Clodronate msds (material safety sheet) Clodronate MSDS. Both types of Clophsome ® are offered in the standard suspension form fo rthe convenience of use, the high potency form fo rdosing of high cotent with limited small volume and the lyophilized forms for the long shelf-life. Clodronate is a medicine used to treat a high level of calcium in the blood caused by changes in the body that happen with cancer. Drug information provided by: IBM Micromedex. Parecoxib is predicted to increase the risk of renal impairment when given with clodronate. •realizar periodicamente exames de sangue e da função do fígado. Você está em: It is also called Bonefos, Clasteon, and Loron 520 Clodronate DRUG NAME: Clodronate SYNONYM(S): Clodronate disodium, clodronic acid, Cl 2MDP, dichloromethylene bisphosphonate, disodium clodronate, sodium clodronate COMMON TRADE NAME(S): CLASTEON®, BONEFOS ; OSTAC CLASSIFICATION: Bone metabolism regulator. It is used to treat hypercalcemia (high blood calcium) for people who have cancer. Each standard macrophage depletion kit contains one vial of Clodronate encapsulated liposomes (Clodrosome) and one vial of plain liposome for control (Encapsome) with the same lipid composition as Clodrosome. Popular Products. This content does not have an Arabic version. By mouth. Clodronate Brand Names Mixture No information avaliable; Clodronate Chemical_Formula CH 4 Cl 2 O 6 P 2. Copyright © 2021 IBM Watson Health. For Adult. © 1998-2021 Mayo Foundation for Medical Education and Research (MFMER). 12 Equine Key Opinions Leaders in English Performance, Western Performance, Adverse reactions include renal insufficiency and hypocalcaemia. Portions of this document last updated: Feb. 01, 2020. setTimeout("$('adwordstopo').hide();", 10000); Injetável (solução) 1500 mg/25 mL: Bonefós. Sodium clodronate (Bonefos, Clasteon, Loron) Sodium clodronate is a type of bisphosphonate. About Us. GU = Gut (intestines) Mayo Clinic does not endorse companies or products. Name of the medicine. Clodronate also treats the weakening in the bones when cancer has spread to the bones from another part of the body. Clodronato dissódico (solução) 300 mg/5 mL – Infusão intravenosa. Sodium clodronate (as tetrahydrate). •evitar deitar por pelo menos 30 minutos. Osteolytic lesions, hypercalcaemia and bone pain associated with skeletal metastases in patients with breast cancer or multiple myeloma. Purified talc, calcium stearate, anhydrous colloidal silica, lactose, gelatin, purified water, iron oxide red, iron oxide yellow, Tekprint SW-9008 black ink and titanium dioxide. Severity of interaction: Moderate Evidence for interaction: Study. Many drugs have more than one name and, therefore, the same drug may be listed more than once. Bulk solution: phosphate buffered saline (20mM sodium phosphate, 09wt% NaCl), pH 7.0-7.5 Manufacturers of Clodronate in Pakistan. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Previous Drug Generic - Next Drug Generic. Few diseases are as dehumanizing and as damaging to a … Clodronate is predicted to decrease the effects of parathyroid hormone. Weight: 02 kg: Quantity: 5 ml (5ml Clodronate Liposomes), 10 ml (10ml Clodronate Liposomes), 15 ml (15ml Clodronate Liposomes), 20ml (20ml Clodronate Liposomes), 25 ml (25ml Clodronate Liposomes), 30 ml (30ml Clodronate Liposomes), 40 ml (40ml Clodronate Liposomes), 50 ml (50ml Clodronate Liposomes), 60 ml (60ml Clodronate Liposomes), 70 ml (70ml Clodronate Liposomes), 80 ml (80ml Clodronate … classificação não disponibilizada; não usar. All rights reserved. •interromper o tratamento se ocorrer comprometimento da função dos rins. Developer and worldwide provider of clodronate liposomes: Delivery on demand + Worldwide shipping & Easy Online Ordering 24/7 - Please Contact Us hipercalcemia devido a tumores malignos ou metástases ósseas; osteólise (dissolução do osso) devido a metástase de tumores sólidos (câncer de mama, próstata ou tireoide) ou devido a neoplasia sanguínea (mieloma múltiplo). temperatura ambiente (15 - 25°C): 24 horas. Volume: 500 mL. Patients must be adequately hydrated before treatment and renal function must be monitored. 1. Treatment for: Breast Cancer, Adjuvant. You might have it as a treatment for a number of cancers that affect the bones such as myeloma and secondary breast cancer. Reúne recursos indispensáveis e conteúdos de ponta contextualizados à realidade brasileira, sendo a melhor ferramenta de consulta para tomada de decisões rápidas e eficazes. •pode ter sua ação diminuída por: alimento com alto teor de cálcio (leite e laticínios); antiácido; droga contendo ferro, cálcio ou magnésio. Genérico: não clodronato dissódico tetraidratado equivalente a clodronato dissódico Uso oral. dados não disponibilizados; não amamentar. Estabilidade após diluição com Cloreto de Sódio 0,9% ou Glicose 5%. It is also used to treat the increased amount of calcium in the blood (hypercalcemia) that may occur with some kinds of cancer. Clodronate (clodronate disodium, Bonefos®) is a non-nitrogen-containing bisphosphonate that inhibits osteoclast activity, and thereby inhibits bone resorption. 1600 mg por dia, em dose única. Clodronate sodium, also called clodronate disodium, is the disodium salt of a nitrogen-free bisphosphonate analog of naturally occurring pyrophosphate. Injetável (solução) 1500 mg/25 mL: Bonefós Injetável (solução) 300 mg/5 mL: Bonefós O que é You may have sodium clodronate for 1 of the following reasons: to treat high blood calcium (hypercalcaemia) The bad news is that clodronate is not directly available in the United States. medicamentos C. setTimeout("$('adwords').hide();", 10000); Estabilidade após diluição com Cloreto de Sódio 0,9% temperatura ambiente (15 - 25°C): eliminação de proteínas pela urina; insuficiência renal aguda após administração intravenosa. Who? For SODIUM CLODRONATE. Cancer. Clodronate works by reducing the breakdown of bone.This medication may be available under multiple brand names and/or in several different forms. refrigeração (2-8°C): 24 horas. Bonefos Bayer, United Kingdom; Bayer, Tunisia; Er-Kim, Turkey; IFET, Greece Drug information provided by: IBM Micromedex. Hematológico: diminuição do cálcio no sangue. Bonefos (clodronate) is a non-amino bisphosphonate intended to reduce the occurrence of bone metastases in the post-surgical (adjuvant) treatment of breast cancer patients. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. BV = Blood vessels (circulation) BR = Brain. Brand Name: Clophosome ® Active: clodronate disodium. Kanis JA(1), McCloskey EV. •com 1 copo cheio de água, em jejum, pelo menos 30 minutos antes do café da manhã. Descriptions. Clodronate molecules are encapsulated in small MLV liposomes for superior activity, physical and chemical stability, and convenience of use and handling. Clodronate is not metabolised and most of the dose appears in the urine within a few days. MF: CH2Cl2O6P2Na2, MW: 288.86.